Tag

Homocysteine

9 genetic variants with this tag.

RSID	Gene	Description	Category
rs1801133	MTHFR C677T	Key enzyme for converting folate to its active methylfolate form	Methylation & Detox	Methylation Folate B Vitamins	Established
rs1801131	MTHFR A1298C	Second MTHFR variant affecting enzyme activity in the regulatory domain	Methylation & Detox	Methylation Folate B Vitamins	Moderate
rs1801394	MTRR A66G	B12 recycling enzyme — regenerates active B12 for the methylation cycle	Methylation & Detox	Methylation B Vitamins Homocysteine	Moderate
rs1805087	MTR A2756G	Methionine synthase — uses B12 to convert homocysteine to methionine	Methylation & Detox	Methylation B Vitamins Homocysteine	Moderate
rs234706	CBS C699T	Common synonymous variant in the CBS gene associated with reduced cardiovascu...	Methylation & Detox	Methylation Cardiovascular Folate	Moderate
rs1801181	CBS A360A	A synonymous variant in CBS affecting homocysteine metabolism and associated ...	Methylation & Detox	Methylation Homocysteine B Vitamins	Moderate
rs567754	BHMT BHMT-02	Intronic variant in betaine-homocysteine methyltransferase gene associated wi...	Methylation & Detox	Methylation Homocysteine B Vitamins	Moderate
rs819147	AHCY	Regulatory variant affecting S-adenosylhomocysteine hydrolase expression, inf...	Methylation & Detox	Methylation Homocysteine Cardiovascular	Moderate
rs1801198	TCN2 Pro259Arg (C776G)	Transcobalamin II variant affecting cellular delivery of vitamin B12 via holo...	Nutrition & Metabolism	Vitamin B12 B Vitamins Methylation	Strong