Tag

Hypertension

10 genetic variants with this tag.

RSID	Gene	Description	Category
rs5443	GNB3 C825T	Synonymous exon-10 variant that triggers alternative splicing of the G-protei...	Hormones & Sleep	Hypertension Blood Pressure Antidepressants	Strong
rs1801253	ADRB1 Arg389Gly	Beta-1 adrenergic receptor variant where Arg389 produces higher basal activit...	Fitness & Body	Fitness Cardiovascular Heart Disease	Strong
rs2681472	ATP2B1	Intronic regulatory variant near the PMCA1 calcium pump gene, one of the most...	Heart & Inflammation	Cardiovascular Blood Pressure Hypertension	Strong
rs1799998	CYP11B2 -344C>T	Promoter variant in aldosterone synthase increasing CYP11B2 transcription, as...	Heart & Inflammation	Cardiovascular Blood Pressure Salt Sensitivity	Moderate
rs1801252	ADRB1 Ser49Gly	Beta-1 adrenergic receptor variant at position 49 affecting receptor downregu...	Fitness & Body	Fitness Cardiovascular Exercise Performance	Strong
rs5068	NPPA	3'UTR variant that disrupts miR-425 binding, increasing atrial natriuretic pe...	Heart & Inflammation	Cardiovascular Blood Pressure Hypertension	Strong
rs891512	NOS3	Intronic NOS3 variant that alters splicing factor binding and is associated w...	Nutrition & Metabolism	Nitric Oxide Cardiovascular Hypertension	Moderate
rs12917707	UMOD	Uromodulin promoter variant — strongest GWAS signal for chronic kidney diseas...	Nutrition & Metabolism	Kidney Function Hypertension Cardiovascular	Established
rs4293393	UMOD	UMOD promoter variant affecting uromodulin expression, linked to CKD, salt-se...	Nutrition & Metabolism	Kidney Disease Hypertension Gout	Established
rs1808593	NOS3	Intronic NOS3 variant associated with ankle-brachial index and peripheral art...	Nutrition & Metabolism	Cardiovascular Nitric Oxide Endothelial Health	Moderate