Tag

Immune & Autoimmune

7 genetic variants with this tag.

RSID	Gene	Description	Category
rs2187668	HLA-DQA1 DQ2.5 tag	Tag SNP for HLA-DQ2.5 haplotype, the strongest genetic risk factor for celiac...	Immune & Gut	Immune & Autoimmune Celiac Disease Gluten Sensitivity	Established
rs7454108	HLA-DQB1 DQ8 tag	Tag SNP identifying HLA-DQ8 haplotype, second strongest genetic risk factor f...	Immune & Gut	Immune & Autoimmune Celiac Disease Type 1 Diabetes	Established
rs1800896	IL10 -1082 A>G	Promoter variant affecting IL-10 production — the master anti-inflammatory cy...	Immune & Gut	Immune & Autoimmune Inflammation Autoimmune	Strong
rs1800629	TNF -308 G>A	Promoter variant increasing TNF-alpha production 2-3 fold, associated with au...	Immune & Gut	Immune & Autoimmune Inflammation Drug Metabolism	Strong
rs3087243	CTLA4 CT60	Immune checkpoint regulatory variant in the 3'UTR affecting T-cell activation...	Immune & Gut	Immune & Autoimmune Thyroid Diabetes	Strong
rs2004640	IRF5 G198T	Intronic variant creating alternative splice site that increases type I inter...	Immune & Gut	Immune & Autoimmune Inflammation Interferon	Strong
rs1800872	IL10 -592 C>A	Promoter variant affecting IL-10 production — a key anti-inflammatory cytokin...	Heart & Inflammation	Inflammation Cardiovascular Immune & Autoimmune	Strong