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rs1042522
|
TP53
Pro72Arg
|
p53 codon 72 polymorphism producing two functionally distinct proteins — Arg7...
|
Longevity & Aging
|
|
Strong
|
|
rs11555236
|
SIRT3
|
Intronic regulatory variant near the SIRT3 VNTR enhancer — the A allele incre...
|
Longevity & Aging
|
|
Moderate
|
|
rs659366
|
UCP2
|
Promoter variant at position -866 of UCP2 that controls mitochondrial uncoupl...
|
Longevity & Aging
|
|
Moderate
|
|
rs8192678
|
PPARGC1A
Gly482Ser
|
Master mitochondrial biogenesis regulator — Ser482 variant reduces PGC-1alpha...
|
Longevity & Aging
|
|
Strong
|
|
rs7181866
|
GABPB1
|
Intronic variant in the mitochondrial biogenesis regulator NRF2, associated w...
|
Fitness & Body
|
|
Moderate
|
|
rs547025
|
SIRT3
|
Intronic variant in SIRT3 (the principal mitochondrial deacetylase) associate...
|
Fertility & Reproductive Health
|
|
Moderate
|
|
rs4880
|
SOD2
Val16Ala
|
Primary mitochondrial antioxidant enzyme - variant reduces superoxide detoxif...
|
Methylation & Detox
|
|
Strong
|
|
rs6949152
|
NRF1
|
Intronic variant in the master mitochondrial biogenesis transcription factor ...
|
Longevity & Aging
|
|
Moderate
|
|
rs2267668
|
PPARD
Intron variant (5' region)
|
Intronic PPARD variant that impairs aerobic fitness gains and body compositio...
|
Fitness & Body
|
|
Moderate
|
|
rs2402970
|
NRF1
|
Intronic NRF1 variant associated with baseline differences in ventilatory thr...
|
Longevity & Aging
|
|
Moderate
|
|
rs1800849
|
UCP3
-55C>T
|
Promoter variant in skeletal muscle uncoupling protein 3 that increases UCP3 ...
|
Nutrition & Metabolism
|
|
Moderate
|
|
rs1937
|
TFAM
S12T
|
Missense variant in the TFAM mitochondrial targeting sequence — the C allele ...
|
Longevity & Aging
|
|
Moderate
|
|
rs10838738
|
MTCH2
|
Intronic GWAS obesity variant in MTCH2 — affects mitochondrial energy balance...
|
Nutrition & Metabolism
|
|
Moderate
|