Tag

Phase I

8 genetic variants with this tag.

RSID	Gene	Description	Category
rs1048943	CYP1A1 Ile462Val (*2C)	Phase I detoxification enzyme that activates polycyclic aromatic hydrocarbons...	Methylation & Detox	Phase I	Strong
rs4646903	CYP1A1 *2A (MspI, T3801C)	Regulatory variant in the 3'-flanking region of CYP1A1 that increases gene in...	Dental & Oral Health	Phase I	Moderate
rs1056836	CYP1B1 Leu432Val	Phase I detoxification enzyme that hydroxylates estradiol to potentially geno...	Methylation & Detox	Phase I	Moderate
rs1341162	CYP2C8	Intronic CYP2C8 haplotype-tagging variant linked to altered drug metabolism c...	Pharmacogenomics	Phase I	Moderate
rs4646438	CYP3A4 *6 (17776insA / frameshift)	Frameshift insertion in CYP3A4 exon 9 that produces a truncated, non-function...	Pharmacogenomics	Phase I	Strong
rs4646976	CYP2E1	CYP2E1 intronic haplotype tag — affects enzyme activity and susceptibility to...	Pharmacogenomics	Phase I	Moderate
rs67784355	CYP3A4 *11 (Thr363Met)	Rare missense variant in CYP3A4 that reduces protein expression and enzymatic...	Pharmacogenomics	Phase I	Emerging
rs72547516	CYP1A2 Ile386Val	Rare CYP1A2 missense variant (Ile386Val) associated with potentially reduced ...	Pharmacogenomics	Phase I	Emerging