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rs1049353
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CNR1
3'UTR (G1359A)
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Synonymous exon 4 variant in the cannabinoid receptor 1 gene; near an exon sp...
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Mood & Behavior
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Moderate
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rs10482605
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NR3C1
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NR3C1 promoter variant reducing glucocorticoid receptor transcription; G alle...
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Longevity & Aging
|
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Moderate
|
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rs10515522
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NR3C1
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Intronic NR3C1 variant associated with longevity in Polish nonagenarians and ...
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Longevity & Aging
|
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Emerging
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rs12402521
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PDC
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Intronic PDC variant in the phosducin gene — G homozygotes show 12–15 mmHg hi...
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Coronary Artery Disease & Atherosclerosis
|
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Moderate
|
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rs12624433
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SLC12A5
KCC2 Chloride Transport
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Intronic variant in SLC12A5 reducing KCC2 potassium-chloride cotransporter fu...
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Mood & Behavior
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Moderate
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rs1743963
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SGK1
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Intronic SGK1 variant associated with depression susceptibility in coronary h...
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Blood Pressure & Hypertension
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Emerging
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rs11545787
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RASD1
RASD1 photic entrainment variant
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3' UTR variant in RASD1 (Dexras1), a GTPase that gates light signals to the c...
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Hormones & Sleep
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Strong
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rs1545843
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SLC6A15
SLC6A15 depression risk variant
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Intronic variant reducing SLC6A15 expression in hippocampus; AA carriers show...
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Mood & Behavior
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Strong
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rs137852689
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STAR
R217T (Arg217Thr)
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Pathogenic STAR variant that abolishes steroidogenic acute regulatory protein...
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Reproductive Hormones
|
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Established
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rs16147
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NPY
C-399T
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Promoter variant in neuropeptide Y that modulates NPY expression under stress...
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Mood & Behavior
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Moderate
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rs258750
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NR3C1
NR3C1 Intronic Variant (c.2181+244A>G)
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Intronic NR3C1 variant tagging glucocorticoid receptor gene haplotype blocks ...
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Reproductive Hormones
|
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Moderate
|
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rs2023239
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CNR1
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Intronic variant near the CNR1 exon 3 alternative promoter that modulates CB1...
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Mood & Behavior
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Moderate
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rs2883929
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NR3C2
NR3C2 I3 intron variant
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Intronic variant in the mineralocorticoid receptor gene associated with alter...
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Reproductive Hormones
|
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Moderate
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rs11683424
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DNMT3A
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Intronic variant in the de novo DNA methyltransferase DNMT3A, associated with...
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Methylation & Detox
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Emerging
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rs324420
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FAAH
Pro129Thr
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Affects anandamide levels through altered FAAH enzyme stability, influencing ...
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Mood & Behavior
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Strong
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rs35936514
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LHPP
LHPP depression risk variant
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Intronic/3'UTR variant in LHPP, a histidine phosphatase essential for stress ...
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Mood & Behavior
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Strong
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rs41423247
|
NR3C1
BclI
|
Intronic glucocorticoid receptor variant affecting cortisol sensitivity and s...
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Mood & Behavior
|
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Strong
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rs4570625
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TPH2
G-703T
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Promoter variant affecting brain serotonin synthesis enzyme; influences emoti...
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Mood & Behavior
|
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Moderate
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rs6757908
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EIF2AK3-AS1
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Rare intronic variant in EIF2AK3-AS1, an antisense long non-coding RNA that r...
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Endometriosis & Uterine Health
|
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Emerging
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rs72704544
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GPM6A
GPM6A Neuronal Membrane Glycoprotein
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Intronic variant in the neuronal membrane glycoprotein M6a gene — a stress-do...
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Mood & Behavior
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Moderate
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rs9556979
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STK24
HPA Axis Regulation
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Regulatory variant near STK24 (MST3), a kinase essential for hippocampal neur...
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Mood & Behavior
|
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Moderate
|
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rs6198
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NR3C1
9β
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3'UTR variant that increases glucocorticoid-resistant GRβ isoform expression,...
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Longevity & Aging
|
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Strong
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rs9470080
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FKBP5
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Intronic FKBP5 variant in the stress-aging haplotype block — T allele carrier...
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Longevity & Aging
|
|
Strong
|
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rs9402571
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SGK1
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Regulatory variant in SGK1 (serum/glucocorticoid regulated kinase 1) — the mi...
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Blood Sugar & Diabetes
|
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Moderate
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