Tag

Vitamin D

19 genetic variants with this tag.

RSID	Gene	Description	Category
rs4588	GC Thr436Lys	Alters vitamin D binding protein affinity, affecting total and bioavailable 2...	Nutrition & Metabolism	Vitamin D Bone Health Cardiovascular	Strong
rs7041	GC Asp432Glu	Vitamin D binding protein variant that determines VDBP isoform, affecting vit...	Nutrition & Metabolism	Vitamin D Bone Health Diet	Strong
rs12785878	DHCR7 Near gene T>G	Influences vitamin D synthesis by regulating how much 7-dehydrocholesterol is...	Nutrition & Metabolism	Vitamin D Bone Health Immune System	Strong
rs1426654	SLC24A5 Ala111Thr	Sodium/potassium/calcium exchanger that regulates melanin production in skin ...	Skin & Eyes	Skin Pigmentation Ancestry Vitamin D	Established
rs2228570	VDR FokI C>T	Vitamin D receptor start codon variant — determines receptor protein length a...	Nutrition & Metabolism	Vitamin D Bone Health Diet	Strong
rs1805007	MC1R R151C	Strongest "R" allele in the melanocortin-1 receptor, shifting pigment from ph...	Skin & Eyes	Pain Sensitivity Skin Health Anesthesia	Established
rs1800012	COL1A1 Sp1 Binding Site	Sp1 transcription factor binding site polymorphism affecting collagen product...	Fitness & Body	Bone & Joint Osteoporosis Calcium	Strong
rs2275913	IL17A -197G>A	Promoter variant in the NFAT binding site that increases IL-17A transcription...	Immune & Gut	Immune & Gut Immune & Autoimmune Inflammation	Strong
rs3736228	LRP5 A1330V	Wnt signaling co-receptor variant affecting bone mineral density and fracture...	Fitness & Body	Bone & Joint Osteoporosis Cardiovascular	Strong
rs3801387	WNT16	Intronic variant affecting cortical bone thickness, bone mineral density, and...	Fitness & Body	Bone & Joint Cardiovascular Diet	Established
rs9594759	TNFSF11	Regulatory variant in the RANKL gene affecting bone mineral density and osteo...	Fitness & Body	Bone & Joint Cardiovascular Calcium	Strong
rs2943641	IRS1 Near-gene C>T	Regulates insulin signaling efficiency and cellular glucose uptake	Nutrition & Metabolism	Diabetes Insulin Cardiovascular	Strong
rs2104286	IL2RA	Intronic variant affecting IL-2 receptor alpha chain expression and soluble I...	Immune & Gut	Immune & Gut Autoimmune Type 1 Diabetes	Strong
rs3135388	HLA-DRA Tag for DRB1*15:01	Tag SNP for HLA-DRB1*15:01 (physically located near HLA-DRA), the strongest g...	Immune & Gut	Immune & Gut Immune & Autoimmune HLA	Established
rs7940244	NADSYN1 Near DHCR7	Intronic NADSYN1 variant in the DHCR7/NADSYN1 vitamin D locus; T allele tags ...	Nutrition & Metabolism	Vitamin D Bone Health Immune System	Strong
rs2282679	GC	Intronic GWAS tag variant in the vitamin D binding protein gene, the stronges...	Nutrition & Metabolism	Vitamin D Bone Health Cardiovascular	Established
rs6013897	CYP24A1	Near-gene regulatory variant affecting vitamin D 24-hydroxylase expression — ...	Nutrition & Metabolism	Vitamin D Bone Health Diet	Strong
rs3829251	NADSYN1	Intronic NADSYN1 variant at the DHCR7/NADSYN1 vitamin D locus; A allele was t...	Nutrition & Metabolism	Vitamin D Bone Health Immune System	Strong
rs7944926	DHCR7	Near-gene intronic variant in the DHCR7/NADSYN1 locus on chromosome 11 that t...	Nutrition & Metabolism	Vitamin D Bone Health Immune System	Strong