Tag
Dopamine
13 genetic variants with this tag.
| RSID | Gene | Description | Category | ||
|---|---|---|---|---|---|
| rs104893665 | SPR Arg150Gly | Pathogenic missense variant in sepiapterin reductase that abolishes BH4 biosy... | Vitamins & Nutrient Absorption | Established | |
| rs121917746 | SPR Q119X | Nonsense variant in sepiapterin reductase that abolishes BH4 biosynthesis, ca... | Vitamins & Nutrient Absorption | Established | |
| rs10839553 | CCKBR | Intronic variant near the cholecystokinin B receptor gene associated with res... | Neurology & Cognition | Strong | |
| rs1611115 | DBH -1021C>T | Strongest known genetic determinant of dopamine beta-hydroxylase activity, co... | Mood & Behavior | Strong | |
| rs1800497 | DRD2/ANKK1 TaqIA (Glu713Lys) | Reduces dopamine D2 receptor density in the striatum, affecting reward proces... | Mood & Behavior | Strong | |
| rs1800955 | DRD4 -521C>T | Promoter variant that modulates dopamine D4 receptor expression in the prefro... | Mood & Behavior | Moderate | |
| rs7647305 | ETV5 | GWAS obesity locus near ETV5 | Appetite & Obesity | Moderate | |
| rs3923809 | BTBD9 | Second independent intronic BTBD9 variant associated with restless legs syndr... | Hormones & Sleep | Strong | |
| rs6454674 | CNR1 Near gene (SNP3) | Intronic variant in the cannabinoid receptor 1 gene that modulates substance ... | Mood & Behavior | Moderate | |
| rs806368 | CNR1 | 3'UTR variant in the cannabinoid receptor 1 gene that regulates CB1 expressio... | Mood & Behavior | Moderate | |
| rs387907200 | SPR | Missense/splicing variant in sepiapterin reductase that reduces BH4 biosynthe... | Methylation & Detox | Strong | |
| rs4680 | COMT Val158Met | Dopamine/catecholamine breakdown — affects stress response and methyl donor t... | Methylation & Detox | Established | |
| rs4532 | DRD1 | Regulatory 5'UTR variant in the dopamine D1 receptor gene influencing recepto... | Neurology & Cognition | Moderate |