Tag

Dopamine

17 genetic variants with this tag.

RSID	Gene	Description	Category
rs104893665	SPR Arg150Gly	Pathogenic missense variant in sepiapterin reductase that abolishes BH4 biosy...	Vitamins & Nutrient Absorption	Dopamine	Established
rs10483099	QDPR	Intronic variant near QDPR that affects BH4 recycling efficiency, influencing...	Methylation & Detox	Dopamine	Emerging
rs121917746	SPR Q119X	Nonsense variant in sepiapterin reductase that abolishes BH4 biosynthesis, ca...	Vitamins & Nutrient Absorption	Dopamine	Established
rs121917747	SPR	Nonsense variant in sepiapterin reductase creating a premature stop codon (p....	Vitamins & Nutrient Absorption	Dopamine	Established
rs10839553	CCKBR	Intronic variant near the cholecystokinin B receptor gene associated with res...	Neurology & Cognition	Dopamine	Strong
rs1611115	DBH -1021C>T	Strongest known genetic determinant of dopamine beta-hydroxylase activity, co...	Mood & Behavior	Dopamine	Strong
rs1800497	DRD2/ANKK1 TaqIA (Glu713Lys)	Reduces dopamine D2 receptor density in the striatum, affecting reward proces...	Mood & Behavior	Dopamine	Strong
rs1800955	DRD4 -521C>T	Promoter variant that modulates dopamine D4 receptor expression in the prefro...	Mood & Behavior	Dopamine	Moderate
rs578776	CHRNA3 3' UTR	CHRNA3 3' UTR variant at 15q25.1 Locus 2 — mechanistically distinct from rs10...	Mood & Behavior	Dopamine	Strong
rs6454674	CNR1 Near gene (SNP3)	Intronic variant in the cannabinoid receptor 1 gene that modulates substance ...	Mood & Behavior	Dopamine	Moderate
rs7647305	ETV5	GWAS obesity locus near ETV5 — affects hypothalamic appetite regulation and f...	Appetite & Obesity	Dopamine	Moderate
rs806368	CNR1	3'UTR variant in the cannabinoid receptor 1 gene that regulates CB1 expressio...	Mood & Behavior	Dopamine	Moderate
rs3923809	BTBD9	Second independent intronic BTBD9 variant associated with restless legs syndr...	Hormones & Sleep	Dopamine	Strong
rs387907200	SPR	Missense/splicing variant in sepiapterin reductase that reduces BH4 biosynthe...	Methylation & Detox	Dopamine	Strong
rs4680	COMT Val158Met	Dopamine/catecholamine breakdown — affects stress response and methyl donor t...	Methylation & Detox	Dopamine	Established
rs4532	DRD1	Regulatory 5'UTR variant in the dopamine D1 receptor gene influencing recepto...	Neurology & Cognition	Dopamine	Moderate
rs9394502	BTBD9 BTBD9 insomnia/RLS variant	Intronic variant in the canonical restless legs syndrome gene BTBD9, associat...	Hormones & Sleep	Dopamine	Strong