Tag

Fitness

32 genetic variants with this tag.

RSID	Gene	Description	Category
rs1042713	ADRB2 Arg16Gly	Beta-2 adrenergic receptor variant affecting receptor downregulation, exercis...	Fitness & Body	Fitness	Strong
rs1049434	SLC16A1 A1470T	Primary lactate transporter in skeletal muscle — affects lactate clearance du...	Fitness & Body	Fitness	Moderate
rs1052373	MYBPC3	Cardiac myosin-binding protein variant strongly associated with endurance ath...	Fitness & Body	Fitness	Strong
rs10852521	FTO	FTO intron 1 variant associated with BMI and body fat accumulation, with stro...	Fitness & Body	Fitness	Moderate
rs11549465	HIF1A Pro582Ser	Master regulator of cellular oxygen response influencing endurance capacity, ...	Fitness & Body	Fitness	Strong
rs11842874	MCF2L	Intronic variant in MCF2L that acts as a synovial eQTL — A allele carriers ha...	Fitness & Body	Fitness	Strong
rs12640088	PPARGC1A	Intronic variant in PPARGC1A that may modulate PGC-1alpha expression and mito...	Fitness & Body	Fitness	Emerging
rs12722	COL5A1 C/T 3'UTR	Collagen fibril assembly variant linked to soft tissue injury risk and tendon...	Fitness & Body	Fitness	Moderate
rs2303729	LTBP4	Missense variant in LTBP4 encoding Val194Ile; the A allele (Ile) forms the IA...	Gamete Quality & DNA Repair	Fitness	Strong
rs1421405659	MYBPC1 Leu259Pro	Ultra-rare dominant missense variant in slow skeletal myosin-binding protein ...	Fitness & Body	Fitness	Strong
rs1572312	NFIA-AS2	Long non-coding RNA regulating erythropoiesis, influencing hemoglobin levels ...	Fitness & Body	Fitness	Strong
rs17602729	AMPD1 C34T (Q12X)	Enzyme critical for energy production during high-intensity exercise; deficie...	Fitness & Body	Fitness	Strong
rs1799752	ACE I/D (Alu insertion/deletion)	The causal ACE insertion/deletion structural variant — presence or absence of...	Fitness & Body	Fitness	Strong
rs1800764	ACE Promoter T>C	Upstream promoter-region ACE variant on a separate LD block from the I/D poly...	Fitness & Body	Fitness	Moderate
rs1800795	IL6 -174G/C	Promoter variant controlling interleukin-6 expression — affects inflammation,...	Fitness & Body	Fitness	Strong
rs1801252	ADRB1 Ser49Gly	Beta-1 adrenergic receptor variant at position 49 affecting receptor downregu...	Fitness & Body	Fitness	Strong
rs1801253	ADRB1 Arg389Gly	Beta-1 adrenergic receptor variant where Arg389 produces higher basal activit...	Fitness & Body	Fitness	Strong
rs1805086	MSTN K153R	Affects myostatin's ability to limit muscle growth, influencing muscle mass a...	Fitness & Body	Fitness	Moderate
rs1815739	ACTN3 R577X	Determines presence of alpha-actinin-3 protein in fast-twitch muscle fibers, ...	Fitness & Body	Fitness	Strong
rs2010963	VEGFA G-634C (+405G>C)	Promoter variant affecting VEGF-A expression and angiogenesis, influencing mu...	Fitness & Body	Fitness	Strong
rs2104772	TNC	Affects tenascin C protein levels and elasticity, influencing tendon injury r...	Fitness & Body	Fitness	Strong
rs2402970	NRF1	Intronic NRF1 variant associated with baseline differences in ventilatory thr...	Longevity & Aging	Fitness	Moderate
rs2228001	XPC Lys939Gln	Missense variant in the DNA damage recognition gene XPC that reduces global-g...	Fitness & Body	Fitness	Strong
rs28937900	FKRP L276I	The most common pathogenic mutation in FKRP causing limb-girdle muscular dyst...	Fitness & Body	Fitness	Established
rs4235308	PPARGC1A	Intronic variant in the PGC-1alpha gene linked to population-specific type 2 ...	Fitness & Body	Fitness	Emerging
rs4341	ACE I/D tag SNP	Tag SNP for the ACE insertion/deletion polymorphism — the C allele tracks the...	Fitness & Body	Fitness	Strong
rs62623713	SYPL2 E99G	Low-frequency missense variant in SYPL2 associated with morbid obesity suscep...	Fitness & Body	Fitness	Emerging
rs63749869	RYR1 R4861H (Arg4861His)	RYR1 missense variant causing malignant hyperthermia susceptibility and centr...	Fitness & Body	Fitness	Established
rs699	AGT M235T	Angiotensinogen level variant affecting blood pressure, sodium sensitivity, a...	Fitness & Body	Fitness	Strong
rs7181866	GABPB1	Intronic variant in the mitochondrial biogenesis regulator NRF2, associated w...	Fitness & Body	Fitness	Moderate
rs6949152	NRF1	Intronic variant in the master mitochondrial biogenesis transcription factor ...	Longevity & Aging	Fitness	Moderate
rs8192678	PPARGC1A Gly482Ser	Master mitochondrial biogenesis regulator — Ser482 variant reduces PGC-1alpha...	Longevity & Aging	Fitness	Strong