Tag

Xenobiotics

9 genetic variants with this tag.

RSID	Gene	Description	Category
rs1048943	CYP1A1 Ile462Val (*2C)	Phase I detoxification enzyme that activates polycyclic aromatic hydrocarbons...	Methylation & Detox	Xenobiotics	Strong
rs2032582	ABCB1 G2677T/A (Ser893Ala/Thr)	Triallelic missense variant in the P-glycoprotein efflux pump that reduces th...	Gamete Quality & DNA Repair	Xenobiotics	Moderate
rs4646903	CYP1A1 *2A (MspI, T3801C)	Regulatory variant in the 3'-flanking region of CYP1A1 that increases gene in...	Dental & Oral Health	Xenobiotics	Moderate
rs1208	NAT2 R268K	NAT2 acetylation speed tag SNP - marks rapid vs slow acetylator haplotypes	Methylation & Detox	Xenobiotics	Established
rs1799930	NAT2 R197Q	Slow acetylator variant affecting Phase II detoxification capacity	Methylation & Detox	Xenobiotics	Established
rs1801280	NAT2 I114T	Phase II detoxification - acetylation of aromatic amines and certain medications	Methylation & Detox	Xenobiotics	Established
rs366631	GSTM1 Tag SNP for gene deletion	Tag SNP proxy for GSTM1 gene deletion status — the most common pharmacogenomi...	Methylation & Detox	Xenobiotics	Strong
rs2602899	ADH5 ADH5 Promoter NF-kB Variant	Regulatory SNP in the ADH5 promoter at a potential NF-kB binding site; the pr...	Allergy & Atopic Disease	Xenobiotics	Moderate
rs71748309	GSTT1 Null (Gene Deletion)	Complete deletion of the GSTT1 gene eliminating glutathione conjugation capac...	Methylation & Detox	Xenobiotics	Strong