Tag

Blood Pressure

47 genetic variants with this tag.

RSID	Gene	Description	Category
rs1008899	NEDD4L	Intronic NEDD4L variant; the G allele associates with reduced blood pressure ...	Blood Pressure & Hypertension	Blood Pressure	Moderate
rs1036477	FBN1	Deep intronic FBN1 variant associated with larger ascending aortic dimensions...	Cardiomyopathy & Structural Heart	Blood Pressure	Strong
rs10177833	SLC4A5	Intronic variant in the sodium bicarbonate cotransporter gene strongly associ...	Blood Pressure & Hypertension	Blood Pressure	Strong
rs10958409	SOX17	Intergenic variant near SOX17 at 8q11 that reduces expression of this endothe...	Vascular Inflammation & Remodeling	Blood Pressure	Strong
rs11556924	ZC3HC1 R363H	Missense variant in ZC3HC1/NIPA altering cell cycle regulation; the T (His363...	Coronary Artery Disease & Atherosclerosis	Blood Pressure	Strong
rs1173771	NPR3 NPR3 promoter variant	Regulatory variant downstream of the NPR3 gene that reduces natriuretic pepti...	Blood Pressure & Hypertension	Blood Pressure	Strong
rs2911463	PIEZO1	Intronic variant in PIEZO1, the endothelial mechanosensory ion channel that s...	Arrhythmia & Heart Rhythm	Blood Pressure	Strong
rs12402521	PDC	Intronic PDC variant in the phosducin gene — G homozygotes show 12–15 mmHg hi...	Coronary Artery Disease & Atherosclerosis	Blood Pressure	Moderate
rs12606138	NEDD4L	Intronic variant in NEDD4L associated with reading ability and dyslexia susce...	Blood Pressure & Hypertension	Blood Pressure	Moderate
rs13154066	NPR3	Regulatory variant near the NPR3 natriuretic peptide clearance receptor gene ...	Endometriosis & Uterine Health	Blood Pressure	Strong
rs17249754	ATP2B1	Intronic variant in the ATP2B1 calcium pump gene; the common G allele reduces...	Blood Pressure & Hypertension	Blood Pressure	Strong
rs1743963	SGK1	Intronic SGK1 variant associated with depression susceptibility in coronary h...	Blood Pressure & Hypertension	Blood Pressure	Emerging
rs1799998	CYP11B2 -344C>T	Promoter variant in aldosterone synthase increasing CYP11B2 transcription, as...	Blood Pressure & Hypertension	Blood Pressure	Moderate
rs2004776	AGT	Intronic regulatory variant in angiotensinogen intron I that enhances HNF3β t...	Blood Pressure & Hypertension	Blood Pressure	Strong
rs2070699	EDN1 EDN1 G2288T Intronic Variant	Intronic EDN1 variant modulating endothelin-1 expression; the T allele associ...	Blood Pressure & Hypertension	Blood Pressure	Moderate
rs2270915	NPR3 N521D	Missense variant in NPR3 clearance receptor disrupting Gi protein coupling, i...	Blood Pressure & Hypertension	Blood Pressure	Moderate
rs2681472	ATP2B1	Intronic regulatory variant near the PMCA1 calcium pump gene, one of the most...	Blood Pressure & Hypertension	Blood Pressure	Strong
rs35929607	STK39	Intronic variant in the SPAK kinase gene that has been studied for associatio...	Blood Pressure & Hypertension	Blood Pressure	Emerging
rs17514846	FURIN	Intronic regulatory variant modulating FURIN expression via allele-specific D...	Coronary Artery Disease & Atherosclerosis	Blood Pressure	Strong
rs3754777	STK39	Intronic STK39 variant that increases SPAK kinase expression, raising blood p...	Blood Pressure & Hypertension	Blood Pressure	Moderate
rs3755351	ADD2	Intronic variant in beta-adducin associated with hypertension susceptibility ...	Blood Pressure & Hypertension	Blood Pressure	Emerging
rs2651899	PRDM16	Intronic variant in the master regulator of brown/beige fat differentiation, ...	Fat Storage & Energy	Blood Pressure	Moderate
rs3865418	NEDD4L	Intronic NEDD4L variant	Blood Pressure & Hypertension	Blood Pressure	Moderate
rs3918226	NOS3	NOS3 promoter variant that reduces eNOS expression and increases hypertension...	Blood Pressure & Hypertension	Blood Pressure	Strong
rs77924615	UMOD PDILT-UMOD regulatory variant	Intronic regulatory variant physically located in PDILT that controls uromodu...	Uric Acid & Kidney Function	Blood Pressure	Strong
rs4762	AGT T174M	Missense variant in angiotensinogen that increases AGT protein levels and rai...	Blood Pressure & Hypertension	Blood Pressure	Moderate
rs3184504	SH2B3 R262W	Pleiotropic missense variant reducing SH2B3 inhibitory function, increasing b...	Coronary Artery Disease & Atherosclerosis	Blood Pressure	Strong
rs374304304	ASL ASL Arg94Cys	Pathogenic missense variant in argininosuccinate lyase that reduces urea cycl...	Metabolic Enzymes & Rare Disorders	Blood Pressure	Established
rs4961	ADD1 Gly460Trp	Alpha-adducin missense variant that increases renal tubular sodium reabsorpti...	Blood Pressure & Hypertension	Blood Pressure	Strong
rs5051	AGT G-6A	Promoter variant that increases angiotensinogen gene transcription, raising p...	Blood Pressure & Hypertension	Blood Pressure	Strong
rs5068	NPPA	3'UTR variant that disrupts miR-425 binding, increasing atrial natriuretic pe...	Blood Pressure & Hypertension	Blood Pressure	Strong
rs1934953	CYP2C8	Intronic CYP2C8 variant linked to hypertension susceptibility, COPD risk, and...	Pharmacogenomics	Blood Pressure	Emerging
rs5186	AGTR1 A1166C	3' UTR variant in angiotensin II type 1 receptor affecting blood pressure reg...	Blood Pressure & Hypertension	Blood Pressure	Moderate
rs61753993	VWF D141G	Missense variant in von Willebrand factor (p.Asp141Gly) associated with type ...	Von Willebrand & Anticoagulant Proteins	Blood Pressure	Moderate
rs7305099	WNK1 WNK1 intronic variant	Intronic WNK1 variant where the G allele is associated with increased essenti...	Blood Pressure & Hypertension	Blood Pressure	Moderate
rs7571842	SLC4A5	Intronic variant in the renal sodium-bicarbonate cotransporter gene SLC4A5 as...	Blood Pressure & Hypertension	Blood Pressure	Strong
rs822391	ADIPOQ IVS1+407C>T	Intronic variant in the adiponectin gene associated with ischemic stroke risk...	Fat Storage & Energy	Blood Pressure	Moderate
rs699	AGT M235T	Angiotensinogen level variant affecting blood pressure, sodium sensitivity, a...	Fitness & Body	Blood Pressure	Strong
rs700651	BOLL	Intronic variant near the BOLL gene associated with increased intracranial an...	Coronary Artery Disease & Atherosclerosis	Blood Pressure	Moderate
rs932764	PLCE1	Intronic variant in PLCE1 (phospholipase C epsilon 1) associated with elevate...	Endometriosis & Uterine Health	Blood Pressure	Strong
rs2758151	SGK1	Regulatory tagging SNP near SGK1 (serum/glucocorticoid regulated kinase 1) — ...	Blood Sugar & Diabetes	Blood Pressure	Moderate
rs2280275	CYP2J2	Intronic variant in CYP2J2	Pharmacogenomics	Blood Pressure	Moderate
rs5443	GNB3 C825T	Synonymous exon-10 variant that triggers alternative splicing of the G-protei...	Hormones & Sleep	Blood Pressure	Strong
rs653178	SH2B3 ATXN2/SH2B3 12q24 pleiotropic locus	Pleiotropic 12q24 locus variant in SH2B3 (LNK) modulating JAK-STAT cytokine s...	Blood Sugar & Diabetes	Blood Pressure	Strong
rs891512	NOS3	Intronic NOS3 variant that alters splicing factor binding and is associated w...	Methylation & Detox	Blood Pressure	Moderate
rs9402571	SGK1	Regulatory variant in SGK1 (serum/glucocorticoid regulated kinase 1) — the mi...	Blood Sugar & Diabetes	Blood Pressure	Moderate
rs9349379	PHACTR1	Intronic regulatory variant in PHACTR1 that controls endothelin-1 and arteria...	Neurology & Cognition	Blood Pressure	Strong