Tag

Brain Health

9 genetic variants with this tag.

RSID	Gene	Description	Category
rs6265	BDNF Val66Met	Key neurotrophin variant that controls activity-dependent BDNF release, affec...	Brain & Mental Health	Cognition Memory Neuroplasticity	Strong
rs1800497	DRD2/ANKK1 TaqIA (Glu713Lys)	Reduces dopamine D2 receptor density in the striatum, affecting reward proces...	Brain & Mental Health	Dopamine Cognition Neurotransmitters	Strong
rs1800955	DRD4 -521C>T	Promoter variant that modulates dopamine D4 receptor expression in the prefro...	Brain & Mental Health	Cognition Dopamine Neurotransmitters	Moderate
rs17070145	WWC1 Intronic C>T	Influences episodic memory performance and hippocampal function through the K...	Brain & Mental Health	Cognition Memory Alzheimer's	Moderate
rs744373	BIN1	Second strongest genetic risk factor for Alzheimer's disease after APOE, asso...	Brain & Mental Health	Alzheimer's Neurological Risk Memory	Established
rs356182	SNCA	Parkinson's disease GWAS risk variant affecting alpha-synuclein expression an...	Brain & Mental Health	Neurological Risk Parkinson's Neuroprotection	Strong
rs17649553	MAPT H1/H2 Haplotype Tag	Haplotype-tagging variant distinguishing MAPT H1 and H2 clades, affecting ris...	Brain & Mental Health	Neurological Risk Parkinson's Dementia	Strong
rs76904798	LRRK2 5' Regulatory Variant	Common noncoding variant upstream of LRRK2 that increases gene expression in ...	Brain & Mental Health	Parkinson's Neurological Risk Brain Health	Strong
rs1006737	CACNA1C	L-type calcium channel gene variant affecting mood regulation, emotional proc...	Brain & Mental Health	Mental Health Brain Health Mood	Strong