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rs2180439
|
WNT10A
|
Lead SNP at the 20p11 locus, the strongest autosomal genetic risk factor for ...
|
Skin & Eyes
|
|
Established
|
|
rs1061170
|
CFH
Y402H
|
Strongly increases risk of age-related macular degeneration through impaired ...
|
Skin & Eyes
|
|
Established
|
|
rs10490924
|
ARMS2
A69S
|
Second strongest genetic risk factor for age-related macular degeneration, af...
|
Skin & Eyes
|
|
Established
|
|
rs2230199
|
C3
R102G
|
Missense variant in complement C3 increasing risk of age-related macular dege...
|
Skin & Eyes
|
|
Established
|
|
rs2802292
|
FOXO3
|
Longevity-associated intronic enhancer variant with 1.9-fold increased probab...
|
Heart & Inflammation
|
|
Established
|
|
rs4236601
|
CAV1
|
Intergenic variant near caveolin genes affecting primary open-angle glaucoma ...
|
Skin & Eyes
|
|
Strong
|
|
rs2736100
|
TERT
|
Common intron 2 variant in the telomerase gene that influences telomere lengt...
|
Immune & Gut
|
|
Strong
|
|
rs75932628
|
TREM2
R47H
|
Rare missense variant in microglial receptor TREM2 that significantly increas...
|
Brain & Mental Health
|
|
Established
|
|
rs3736228
|
LRP5
A1330V
|
Wnt signaling co-receptor variant affecting bone mineral density and fracture...
|
Fitness & Body
|
|
Strong
|
|
rs17649553
|
MAPT
H1/H2 Haplotype Tag
|
Haplotype-tagging variant distinguishing MAPT H1 and H2 clades, affecting ris...
|
Brain & Mental Health
|
|
Strong
|
|
rs143383
|
GDF5
C/T
|
Regulatory variant in GDF5 affecting cartilage development and osteoarthritis...
|
Fitness & Body
|
|
Established
|
|
rs3025058
|
MMP3
5A/6A
|
Promoter polymorphism affecting MMP3 enzyme expression levels, influencing ca...
|
Fitness & Body
|
|
Strong
|