Tag

Antioxidants

11 genetic variants with this tag.

RSID	Gene	Description	Category
rs6721961	NFE2L2	Promoter variant reducing NRF2 transcriptional activity by >50%, impairing th...	Longevity & Aging	Oxidative Stress Antioxidants Detoxification	Moderate
rs1042522	TP53 Pro72Arg	p53 codon 72 polymorphism producing two functionally distinct proteins — Arg7...	Longevity & Aging	Longevity Aging Cancer Risk	Strong
rs10490924	ARMS2 A69S	Second strongest genetic risk factor for age-related macular degeneration, af...	Skin & Eyes	Eye Health Aging Antioxidants	Established
rs4880	SOD2 Val16Ala	Primary mitochondrial antioxidant enzyme - variant reduces superoxide detoxif...	Methylation & Detox	Detoxification Oxidative Stress Antioxidants	Strong
rs1050450	GPX1 Pro198Leu	Selenium-dependent antioxidant enzyme that neutralizes hydrogen peroxide; the...	Methylation & Detox	Detoxification Oxidative Stress Selenium	Strong
rs1695	GSTP1 Ile105Val	Phase II detoxification enzyme that conjugates glutathione to carcinogens, dr...	Methylation & Detox	Detoxification Glutathione Phase II	Strong
rs1800566	NQO1 Pro187Ser (C609T)	Phase II detoxification enzyme that reduces quinones and recycles CoQ10 to it...	Methylation & Detox	Detoxification Phase II Oxidative Stress	Strong
rs1056836	CYP1B1 Leu432Val	Phase I detoxification enzyme that hydroxylates estradiol to potentially geno...	Methylation & Detox	Detoxification Phase I Estrogen Metabolism	Moderate
rs1001179	CAT -262C>T	Catalase promoter variant affecting hydrogen peroxide clearance and antioxida...	Methylation & Detox	Detoxification Antioxidants Oxidative Stress	Strong
rs11057830	SCARB1	Intronic variant in SCARB1 that affects SR-BI receptor function and the intes...	Nutrition & Metabolism	Vitamin E Vitamins Fat Metabolism	Moderate
rs6133175	SLC23A2	Intronic variant in the tissue vitamin C transporter SVCT2 — GG homozygotes c...	Nutrition & Metabolism	Vitamin C Vitamins Diet	Moderate