Research
Tag

Antioxidants

17 genetic variants with this tag.

RSID Gene Description Category
rs1001179 CAT -262C>T Catalase promoter variant affecting hydrogen peroxide clearance and antioxida... Methylation & Detox Strong
rs10063949 SLC23A1 SLC23A1 variant Intronic variant in the intestinal and renal vitamin C transporter gene (SVCT... Vitamins & Nutrient Absorption Moderate
rs10490924 ARMS2 A69S Second strongest genetic risk factor for age-related macular degeneration, af... Skin & Eyes Established
rs11057830 SCARB1 Intronic variant in SCARB1 that affects SR-BI receptor function and the intes... Cholesterol & Lipoproteins Moderate
rs11057841 SCARB1 Intronic variant in SCARB1 that tags a haplotype affecting SR-BI receptor-med... Cholesterol & Lipoproteins Moderate
rs1050450 GPX1 Pro198Leu Selenium-dependent antioxidant enzyme that neutralizes hydrogen peroxide; the... Methylation & Detox Strong
rs2251780 GSR Intronic variant in the glutathione reductase gene affecting antioxidant defe... Vitamins & Nutrient Absorption Emerging
rs2237583 PON1 PON1 intron variant Intronic PON1 variant that modulates arylesterase activity of the HDL-bound a... Vascular Inflammation & Remodeling Moderate
rs2361502 MROH2A Intronic variant adjacent to the UGT1A gene cluster; C allele tags elevated s... Metabolic Enzymes & Rare Disorders Moderate
rs3877899 SELENOP Ala234Thr Missense variant in selenoprotein P that alters selenium transport capacity; ... Vitamins & Nutrient Absorption Moderate
rs1695 GSTP1 Ile105Val Phase II detoxification enzyme that conjugates glutathione to carcinogens, dr... Methylation & Detox Strong
rs705379 PON1 PON1 promoter -108C>T Promoter polymorphism that controls PON1 gene expression — the T allele (A on... Vascular Inflammation & Remodeling Strong
rs854555 PON1 PON1 3'UTR variant Intronic/downstream PON1 haplotype-tagging variant associated with PON1 activ... Vascular Inflammation & Remodeling Emerging
rs1800566 NQO1 Pro187Ser (C609T) Phase II detoxification enzyme that reduces quinones and recycles CoQ10 to it... Methylation & Detox Strong
rs6133175 SLC23A2 Intronic variant in the tissue vitamin C transporter SVCT2 — GG homozygotes c... Vitamins & Nutrient Absorption Moderate
rs6721961 NFE2L2 Promoter variant reducing NRF2 transcriptional activity by >50%, impairing th... Longevity & Aging Moderate
rs4880 SOD2 Val16Ala Primary mitochondrial antioxidant enzyme - variant reduces superoxide detoxif... Methylation & Detox Strong