Tag

Antioxidants

25 genetic variants with this tag.

RSID	Gene	Description	Category
rs1001179	CAT -262C>T	Catalase promoter variant affecting hydrogen peroxide clearance and antioxida...	Methylation & Detox	Antioxidants	Strong
rs10063949	SLC23A1 SLC23A1 variant	Intronic variant in the intestinal and renal vitamin C transporter gene (SVCT...	Vitamins & Nutrient Absorption	Antioxidants	Moderate
rs1042522	TP53 Pro72Arg	p53 codon 72 polymorphism producing two functionally distinct proteins — Arg7...	Longevity & Aging	Antioxidants	Strong
rs10490924	ARMS2 A69S	Second strongest genetic risk factor for age-related macular degeneration, af...	Skin & Eyes	Antioxidants	Established
rs11057830	SCARB1	Intronic variant in SCARB1 that affects SR-BI receptor function and the intes...	Cholesterol & Lipoproteins	Antioxidants	Moderate
rs11057841	SCARB1	Intronic variant in SCARB1 that tags a haplotype affecting SR-BI receptor-med...	Cholesterol & Lipoproteins	Antioxidants	Moderate
rs11950646	SLC23A1	Intronic variant in the intestinal and renal vitamin C transporter gene (SVCT...	Vitamins & Nutrient Absorption	Antioxidants	Moderate
rs1050450	GPX1 Pro198Leu	Selenium-dependent antioxidant enzyme that neutralizes hydrogen peroxide; the...	Methylation & Detox	Antioxidants	Strong
rs12704795	PON2 PON2 intron 1 variant	Intronic PON2 haplotype tag; the A allele is associated with reduced intracel...	Vascular Inflammation & Remodeling	Antioxidants	Moderate
rs1056836	CYP1B1 Leu432Val	Phase I detoxification enzyme that hydroxylates estradiol to potentially geno...	Methylation & Detox	Antioxidants	Moderate
rs2251780	GSR	Intronic variant in the glutathione reductase gene affecting antioxidant defe...	Vitamins & Nutrient Absorption	Antioxidants	Emerging
rs2361502	MROH2A	Intronic variant adjacent to the UGT1A gene cluster; C allele tags elevated s...	Metabolic Enzymes & Rare Disorders	Antioxidants	Moderate
rs2237583	PON1 PON1 intron variant	Intronic PON1 variant that modulates arylesterase activity of the HDL-bound a...	Vascular Inflammation & Remodeling	Antioxidants	Moderate
rs3877899	SELENOP Ala234Thr	Missense variant in selenoprotein P that alters selenium transport capacity; ...	Vitamins & Nutrient Absorption	Antioxidants	Moderate
rs1695	GSTP1 Ile105Val	Phase II detoxification enzyme that conjugates glutathione to carcinogens, dr...	Methylation & Detox	Antioxidants	Strong
rs1800566	NQO1 Pro187Ser (C609T)	Phase II detoxification enzyme that reduces quinones and recycles CoQ10 to it...	Methylation & Detox	Antioxidants	Strong
rs4729189	PON2	Intronic PON2 variant associated with variation in serum paraoxonase activity...	Vascular Inflammation & Remodeling	Antioxidants	Emerging
rs705379	PON1 PON1 promoter -108C>T	Promoter polymorphism that controls PON1 gene expression — the T allele (A on...	Vascular Inflammation & Remodeling	Antioxidants	Strong
rs6133175	SLC23A2	Intronic variant in the tissue vitamin C transporter SVCT2 — GG homozygotes c...	Vitamins & Nutrient Absorption	Antioxidants	Moderate
rs854555	PON1 PON1 3'UTR variant	Intronic/downstream PON1 haplotype-tagging variant associated with PON1 activ...	Vascular Inflammation & Remodeling	Antioxidants	Emerging
rs854572	PON1 PON1 promoter -909G>C	Promoter polymorphism that modulates PON1 gene expression level — the G allel...	Vascular Inflammation & Remodeling	Antioxidants	Moderate
rs6596471	SLC23A1 SLC23A1 variant	Intronic variant in the intestinal and renal vitamin C transporter gene (SVCT...	Vitamins & Nutrient Absorption	Antioxidants	Moderate
rs6596473	SLC23A1 SLC23A1 variant	Intronic variant in the intestinal and renal vitamin C transporter gene (SVCT...	Vitamins & Nutrient Absorption	Antioxidants	Emerging
rs6721961	NFE2L2	Promoter variant reducing NRF2 transcriptional activity by >50%, impairing th...	Longevity & Aging	Antioxidants	Moderate
rs4880	SOD2 Val16Ala	Primary mitochondrial antioxidant enzyme - variant reduces superoxide detoxif...	Methylation & Detox	Antioxidants	Strong