Tag

Phase II

11 genetic variants with this tag.

RSID	Gene	Description	Category
rs1138272	GSTP1 Ala114Val	Second functional variant in glutathione S-transferase Pi 1, reducing enzyme ...	Methylation & Detox	Phase II	Moderate
rs1208	NAT2 R268K	NAT2 acetylation speed tag SNP - marks rapid vs slow acetylator haplotypes	Methylation & Detox	Phase II	Established
rs1695	GSTP1 Ile105Val	Phase II detoxification enzyme that conjugates glutathione to carcinogens, dr...	Methylation & Detox	Phase II	Strong
rs17309872	GSS	Downstream regulatory variant of glutathione synthetase (GSS) associated with...	Methylation & Detox	Phase II	Moderate
rs1799930	NAT2 R197Q	Slow acetylator variant affecting Phase II detoxification capacity	Methylation & Detox	Phase II	Established
rs1800566	NQO1 Pro187Ser (C609T)	Phase II detoxification enzyme that reduces quinones and recycles CoQ10 to it...	Methylation & Detox	Phase II	Strong
rs1801280	NAT2 I114T	Phase II detoxification - acetylation of aromatic amines and certain medications	Methylation & Detox	Phase II	Established
rs887829	UGT1A1 UGT1A1*80	Promoter variant in UGT1A1 that tags the *28 reduced-expression haplotype; T ...	Vascular Inflammation & Remodeling	Phase II	Strong
rs366631	GSTM1 Tag SNP for gene deletion	Tag SNP proxy for GSTM1 gene deletion status — the most common pharmacogenomi...	Methylation & Detox	Phase II	Strong
rs4148323	UGT1A1 *6 Gly71Arg	Phase II glucuronidation enzyme that metabolizes bilirubin and many drugs inc...	Pharmacogenomics	Phase II	Established
rs71748309	GSTT1 Null (Gene Deletion)	Complete deletion of the GSTT1 gene eliminating glutathione conjugation capac...	Methylation & Detox	Phase II	Strong